NEW DATA ON THE MUSE™ SYSTEM TO BE PRESENTED DURING DIGESTIVE DISEASE WEEK® (DDW) 2017

OMER, Israel, May 4, 2017 — Medigus Ltd. (NASDAQ: MDGS) (TASE: MDGS), a medical device company developing minimally invasive endosurgical tools and a leader in direct visualization technology, today announced that three poster presentations featuring new data on the MUSE™ System will be presented at the upcoming Digestive Disease Week® (DDW), being held in Chicago from May 6-9, 2017.

“We are pleased to have new clinical findings to share at DDW this year, including the interim results from a multi-center trial,” said Chris Rowland, Chief Executive Officer of Medigus. “The data focuses on the outcomes of using MUSE, a minimally invasive solution for GERD. Our system can help reduce the unmet treatment need for patients who fall within the gap between drug therapy and invasive surgical procedures.”

The MUSE system is a single-use flexible transoral stapler that merges the latest advancements in microvisual, ultrasonic and surgical stapling. The device comes equipped with an ultrasonic sight and range finder and a micro ScoutCam™ CMOS camera, which enables a single physician to perform an incisionless transoral fundoplication — the procedure intended to treat the anatomical cause of gastroesophageal reflux disease (GERD).

MUSE Poster Presentations – Tuesday, May 9th at 12:00PM-2PM CT, South Hall (McCormick Place), Poster Session: Esophagus 2

• Transoral Anterior Fundoplication (TAF) with Medigus Ultrasound Surgical Endostapler (MUSETM) for the Treatment of Gastroesophageal Reflux Disease (GERD); 6-Month Results from a Single-Center Prospective Study, during Poster Session # 2680898
Authors: Pier Alberto Testoni1, Sabrina G. Testoni1, Giorgia Mazzoleni1, Lorella Fanti1, Sandro Passaretti1
Institution: 1. San Raffaele Scientific Institute, "Vita-Salute" San Raffaele University, Milan, Mi, Italy.

• Interim Results From A Multi-Center Post-Marketing Surveillance Registry Study for
Endoscopic Anterior Fundoplication, during Post Session Poster Session # 2684455
Authors: Ali Lankarani1, Guido Costamagna2, Ivo Boskoski2, Jose Nieto1, Glen A. Lehman9, Don J. Selzer9, Horst Neuhaus3, Torsten Beyna3, Shinil Shah10, Sheilendra Mehta10, Gregory B. Haber4, Ralf Kiesslich5, Johannes W. Rey5, Anthony Starpoli4, Barham K. Abu Dayyeh7, Stavros N. Stavropoulos6, Karel Caca8, Kenneth J. Chang11, Lorella Fanti12, Pier Alberto Testoni12
Institutions: 1. Boarland-Groover Clinic, Jacksonville , FL, United States.
2. Policlinico A. Gemelli , Rome, Italy.
3. Evangelisches Krankenhaus, Dusseldorf, Germany.
4. NYU Langone Medical Center, New York, NY, United States.
5. Horst Schmidt Kliniken, Ludwigsburg, Germany.
6. Winthrop Hospital, Mineola, NY, United States.
7. Mayo Clinic, Rochester, MN, United States.
8. Kliniken Ludwigsburg, Ludwigsburg, Germany.
9. Indiana University Indianapolis, Indiana , IN, United States.
10. Univ. of Texas Health, Houston, TX, United States.
11. Univ. of CA Irvine, Orange , CA, United States.
12. Ospedale San Raffaele, Milan, Italy.

• Endoscopic Predictors of Decreased Reflux After Endoscopic Anterior Fundoplasty, during Poster Session # 2668308
Authors: Ali Lankarani1, Stuart Kirwan2, Jose Nieto1
Institutions: 1. Borland Groover Clinic, Jacksonville, FL, United States.
2. University of Florida, Gainesville, FL, United States.