Medigus MUSE™ System Study Data to be Featured at ‘Posters in the Spotlight’ Session During United European Gastroenterology Week 2015

OMER, Israel, October 28, 2015 – Medigus Ltd. (NASDAQ: MDGS) (TASE: MDGS), a medical device company developing minimally invasive endosurgical tools and a leader in direct visualization technology, today announced that during United European Gastroenterology Week (UEGW), being held from October 24-28, 2015 in Barcelona, Spain, Dr. Tae-Geun Gweon of Harvard Medical School and Boston Children’s Hospital, Boston, MA, will be presenting findings from a new ex-vivo study conducted together with Dr. Kai Matthes.

This presentation (P1367), Endoscopic Anterior Fundoplication with the Medigus Ultrasonic Surgical Endostapler (MUSE™): Results from an Ex-vivo Simulation Trial to Assess the Efficacy of the Procedure by Comparing Stapling Position and Gastric Yield Pressures, has been selected by UEG to be featured at the Poster in the Spotlight Session: Advances in upper GI endoscopy, and will take place on Wednesday October 28th, 2015 from 8:30 to 10:30 am CET in E-Poster Lounge 2. The MUSE research will be the focus of a 15-minute oral presentation and discussion during the moderated session.

The goal of the new ex-vivo study was to identify the ideal stapling distance, quantity and distribution in relation to the Gastroesophageal Junction (GEJ) in a validated simulation model, using the MUSE system. The preliminary data set to this new ex-vivo study, which was previously presented at the Society of American Gastrointestinal and Endoscopic Surgeons (SAGES) 2015 Annual Meeting, varied the distance of stapling location from the GEJ, and the earlier study had concluded that a distance of at least 3 cm, is ideal for fundoplication procedures conducted using the MUSE system. This new data set follows up to those results to identify the ideal distribution of staplings, by varying the angle between each stapling action, or stapling distribution.

“Endoscopic fundoplication procedures, such as the ones performed with MUSE, are an emerging technique for the treatment of GERD, and I believe can become a leading method for long-term GERD relief,” said Dr. Matthes (MD, PhD), Harvard Medical School and Boston Children’s Hospital, and co-author of this study. “Throughout this study, we have been able to identify the ideal stapling distance and distribution to optimize administration of the MUSE system and enhance patient outcomes.”

To obtain this data set, ten fundoplication procedures using the MUSE system were performed in four groups of ex-vivo porcine stomachs. Three out of four groups received two stapling actions and one group received three stapling actions, varying the distribution between 90 and 180 degrees. Drs. Gweon and Matthes concluded that placement of three staplings at 3 cm proximal to the GEJ with an angle of 90 degrees between each staple position (180 degree partial anterior fundoplication) results in the most effective restoration of the esophageal valve mechanism.

For more information about MUSE, please visit the Medigus booth in Exhibit Hall 8.1, Booth # 92 or visit us online at Medigus.com.