First MUSE™ Procedure Performed in China By Leading Gastroenterologist, Professor Rong Wan

OMER, Israel, March 9, 2017 — Medigus Ltd. (NASDAQ: MDGS) (TASE: MDGS), a medical device company developing minimally invasive endosurgical tools and a leader in direct visualization technology, announced the completion of the first MUSE procedure in China. The procedure was performed by Professor Rong Wan, Department of Gastroenterology, Shanghai First People’s Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China. Prof Wan reported that the procedure was successful, with the patient encountering minimal discomfort during the procedure. The patient has since been released from the hospital, with no procedural complications.

The MUSE system is a single-use flexible transoral stapler that merges the latest advancements in microvisual, ultrasonic and surgical stapling. The device comes equipped with an ultrasonic sight and range finder and a micro ScoutCam™ CMOS camera, which enables a single physician to perform an incisionless transoral fundoplication — the procedure intended to treat the anatomical cause of gastroesophageal reflux disease (GERD). Since the device doesn’t require any incisions, patients generally report greater comfort during procedure and experience reduced hospital stays by up to 50% over invasive fundoplication procedures.

While GERD is already prevalent worldwide, evidence suggests an increase in GERD prevalence since 1995, particularly in North America and East Asia. MUSE has the potential to improve GERD-related quality of life for many of them by addressing the root cause of the disorder, not just offering symptom relief, which many drug therapies do.

“With the completion of our first-in-man MUSE procedure in China we are looking forward to working with leading GIs across the country to implement this procedure and uniquely address the existing gap in GERD treatment between drug therapy and invasive laparoscopic procedures,” said Chris Rowland, CEO of Medigus. “We are honored to partner with Professor Rong Wan, a leading gastroenterologist in Shanghai, who continues to be at the forefront of innovation and sees the potential to offer a less-invasive and more cost-effective option to patients, physicians and the healthcare system.”